One particularly pernicious condition is low morale. Morale is, roughly, "the belief that if you work hard, your conditions will improve." If your morale is low, you can't push through adversity. It's also very easy to accidentally drop your morale through standard rationalist life-optimization. It's easy to optimize for wellbeing and miss out on the factors which affect morale, especially if you're working on something important, like not having everyone die. One example is working at an office that feeds you three meals per day. This seems optimal: eating is nice, and cooking is effort. Obvious choice. Example But morale doesn't come from having nice things. Consider a rich teenager. He gets basically every material need satisfied: maids clean, chefs cook, his family takes him on holiday